Covid vaccination cut risk of adverse heart events, large study finds

[marble falls]

https://www.statnews.com/2026/06/15/covid-vaccination-cardiovascular-protection-jama-study/

Covid vaccination cut risk of adverse heart events, large study finds
Vaccine may be cardioprotective, especially for older adults and those with comorbidities

By Lauren Chan

June 15, 2026

AAAS Mass Media Science & Engineering Fellow

-snip-

The study, published in JAMA Internal Medicine on Monday along with several other Covid-related papers, followed more than 1 million veterans who received flu vaccinations at Veterans Affairs health care facilities in 2024; about a third of them also received a Covid vaccine.

-snip-

To the researchers’ surprise, Covid vaccination was also tied to a nearly 24% reduction in all-cause cardiac events — not just those with a documented Covid diagnosis. The authors said this could translate to prevention of approximately 3,500 major cardiac events and 2,400 deaths annually per 1 million people.

-snip-

While Al-Aly’s findings indicate cardioprotective benefits of Covid vaccines, these results may surprise some because vaccine-related myocarditis — inflammation of the heart muscle — was an early concern about mRNA formulations. The side effect was seen mostly in young men. Notably, studies have found that vaccine-related myocarditis is significantly milder than myocarditis resulting from an actual Covid infection.

-snip-

A study funded by the European Centre for Disease Prevention and Control also released on Monday in JAMA Network Open, indicating similar effectiveness for Covid vaccines in the 2025-2026 season for older European adults. The researchers, including numerous European epidemiologists and public health experts, evaluated individuals 60 years old and above across multiple European countries and found approximately 55% effectiveness in protecting participants from symptomatic disease in the two months after vaccination. While vaccine uptake has decreased in Europe, the authors told STAT that the new annual vaccines are updated based on “COVID-19 vaccine strain(s) that match circulating viruses and thereby are likely to be more effective.” The low uptake rate and high effectiveness of vaccines, the paper says, “suggests missed opportunities for preventing symptomatic COVID-19 among unvaccinated vulnerable groups.”

-snip-






Robert Califf, cardiologist and former commissioner of the Food and Drug Administration has written: “There are many, many studies now that show that vaccinations of various types seem to reduce the risk of chronic diseases, including cardiovascular disease … this is not inconsistent with what the other studies have shown."

[TBF]

1. "Covid vaccination was also tied to a nearly 24% reduction in all-cause cardiac events" --

this is actually pretty amazing, and I will have to read more about this.

I was one of the immune compromised (due to medication) who persisted w/vaccines. I was in a local study, knew what my antibody levels were after each set of vaccines, and knew for example that Moderna vaccines worked much better for someone like me than the Pfizer version (at least initially).

But it definitely was a point of discussion during the time - some immunosuppressed folks weren't sure if they should even get vaccines if they wouldn't be effective (short answer - they were effective - but not necessarily the first set you got).

I was also able to stay inside so I didn't actually contract Covid until I had to travel in late 2022 - by which time there were much better treatments around like Paxlovid (which worked for me).

I am encouraged that the studies are still being done, albeit by private orgs/labs, I don't trust anything coming out of the CDC these days.

[rog]

5. This is a great study, but the conclusion is nuanced.

The article linked above has a link to the original study, which is available in its entirety.

https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2850241?guestAccessKey=d13423b6-0f97-447a-a381-df38354146d7

The conclusion shows some nuance, re: all cause mortality and major cardiac events:

Conclusions

In this nationwide cohort study of veterans, the 2024-2025 COVID-19 vaccine was associated with a lower risk of COVID19–associated MACE; absolute risk reductions were generally modest, but more pronounced in older adults and individuals with comorbidities. Effectiveness extends to broader outcomes (all-cause MACE, hospitalization, and death), likely reflecting the hidden burden of undetected SARS-CoV-2 and associated complications that are reduced by COVID-19 vaccination. These findings provide timely evidence to help inform clinical and public health discussions about the role of updated COVID-19 vaccines in the current epidemiologic context.

If I'm reading this correctly, they appear to be saying that the protective effect extends to cardiac events, morbidity, etc, that are the result of undetected Covid infection, not necessarily to heart disease in general or other conditions unrelated to Covid.

Take a look and let me know if I'm mistaken.

Disclaimer: I am fully vaxxed and up to date, and will continue to do so.

[marble falls]

6. It's a study. Of course it's nuanced. The results will be not be so nuanced once other parties attempt to reproduce ...

... these results.

[rog]

10. I'm seriously not trying to be adversarial ...

... or to start anything. I'm just pointing out something I didn't understand until I read the (very good) study. On first reading I thought the vaccine appeared to be protective for cardiac events in general, but the study actually said it's protective for Covid sequelae, diagnosed and undiagnosed. In other words, the vaccine appears to mitigate the cardiac effects of undiagnosed Covid infections, which is great.

Please correct me if I'm reading this incorrectly, but I think I am not.

All I did was to post a link to the study itself, and to quote the conclusion as a matter of interest and possible clarification. I honesty didn't intend to raise any dust.

Take care ...

[marble falls]

7. I was one of the first cases in my town, Thanksgiving 2019. Five months after my bladder cancer surgery ...

... I was in hospital for over a week. When I got there, there was no one on that ward, when I left not only was the whole hallway filed, but there were barriers at each door with a sign that said no one was to enter without protective gear. The diagnosis was "unknown rhinovirus". I was immunocompromised from my Cancer adventure. I do not want to be that sick again, ever.

I support vaxx and have had all covid vaxxes VA hands out. No problem.

[underpants]

2. 👍

[ProfessorGAC]

3. A Positive Side-Effect!

Guess I'll continue getting one each fall.
This study is going to make someone most unhappy. You know who I mean!

[rampartd]

4. these dolts are killing thousands to ''save" hand fulls.

Notably, studies have found that vaccine-related myocarditis is significantly milder than myocarditis resulting from an actual Covid infection.

[31j20b3]

8. It sounds like a result from the V.A.'s Million Vet Program...

I've been part of that since they began enrolling volunteers... seemed like the least I could do in return for the care they've given me

To those who don't know, the Million Vet program creates links between vets genetic profiles and their VA medical records. It was one of the first of the large scale databases to do that. There are now several more that involve civilian volunteers genetics and their private medical records.

Data on these scales is a powerful research tool... I'm glad people are participating in these

[marble falls]

12. This information was part of the study's input.

[Blue_Roses]

11. This is very interesting

and good news...
I'm guilty of not staying up-to-date on all my vaccines. I had a stroke a year ago, so I'm really trying to be more diligent with my healthcare.

Thank- you for this

(Oh and good job with the bait. This LG person is nuts. I can't keep up with all her shenanigans. You guys are good!)

[marble falls]

13. My favorite catch happened a decade ago, someone posted about the death of the Long Island Medium's ...

... husband and my reply was "How did she not see that coming." LG lost her mind.

[Blue_Roses]

14. This has been going on

for a decade?

[marble falls]

15. No, absolutely not ...

... more like twenty. There are members here who have seen her, talked with her, socialized. Free VPNs and server swapping to all over the planet has it's downsides, too. She has full days to do nothing but this. She gets a kick from how long she stays on. Sort of the DU Rodeo. She has a"boyfriend" who has posted, but I don't know that I've ever seen it.

There used to be more, she's about the last. The other group, Jackpine Radicals are from a site started by ex DUers and since their site died three or four years ago, some try to come back. You look for bothsiderism, "Third-Way"ism.

[DFW]

16. This is nice, but

It‘s all percentages and indications. My Covid vaccinations are current, but I am nevertheless in the middle of a sequence of heart surgeries that no vaccine has served to alleviate.