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Malaria trial shows 'striking' 70% reduction in severe illness in children
Related: Seasonal Malaria Vaccination with or without Seasonal Malaria Chemoprevention (New England Journal of Medicine)
Also: Trial suggests malaria sickness could be cut by 70% (BBC)
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Source: The Guardian
Malaria trial shows ‘striking’ 70% reduction in severe illness in children
A study in Burkina Faso and Mali suggests combining anti-malarial drugs and vaccination could reduce deaths and hospitalisations
Saeed Kamali Dehghan
Thu 26 Aug 2021 17.05 BST
A trial combining vaccinations and prevention drugs has substantially lowered the number of children dying of malaria in two African countries, according to researchers.
The results of the study, published in the New England Journal of Medicine, have been hailed as “very striking”, especially at a time when decades-long progress on combating malaria has stalled in some countries.
Led by the London School of Hygiene & Tropical Medicine (LSHTM), the trial showed a 70% reduction in hospitalisation or death when young children were given both seasonal vaccinations and antimalarial drugs compared to using just one intervention.
Researchers believe the approach could prevent some of the 400,000 deaths from the mosquito-borne disease every year, most of them children. In 2019, more than 90% of the estimated 230m cases of malaria occurred in Africa.
-snip-
A study in Burkina Faso and Mali suggests combining anti-malarial drugs and vaccination could reduce deaths and hospitalisations
Saeed Kamali Dehghan
Thu 26 Aug 2021 17.05 BST
A trial combining vaccinations and prevention drugs has substantially lowered the number of children dying of malaria in two African countries, according to researchers.
The results of the study, published in the New England Journal of Medicine, have been hailed as “very striking”, especially at a time when decades-long progress on combating malaria has stalled in some countries.
Led by the London School of Hygiene & Tropical Medicine (LSHTM), the trial showed a 70% reduction in hospitalisation or death when young children were given both seasonal vaccinations and antimalarial drugs compared to using just one intervention.
Researchers believe the approach could prevent some of the 400,000 deaths from the mosquito-borne disease every year, most of them children. In 2019, more than 90% of the estimated 230m cases of malaria occurred in Africa.
-snip-
Read more: https://www.theguardian.com/global-development/2021/aug/26/malaria-trial-shows-striking-70-reduction-in-severe-illness-in-children
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Source: BBC
Trial suggests malaria sickness could be cut by 70%
By Philippa Roxby
Health reporter
26 August 2021
A new approach to protecting young African children from malaria could reduce deaths and illness from the disease by 70%, a study suggests.
Giving them vaccines before the worst season in addition to preventative drugs produced "very striking" results, London researchers say.
The trial followed 6,000 children aged under 17 months in Burkina Faso and Mali.
Most of the 400,000 deaths from malaria each year are in the under-fives.
And the mosquito-borne disease is still a major health issue in many parts of sub-Saharan Africa.
This trial, published in the New England Journal of Medicine, focused on giving very young children a vaccine already in use and anti-malarial drugs at the time of year they are most vulnerable - often the rainy season (from June in Burkina Faso), when mosquitoes multiply.
-snip-
By Philippa Roxby
Health reporter
26 August 2021
A new approach to protecting young African children from malaria could reduce deaths and illness from the disease by 70%, a study suggests.
Giving them vaccines before the worst season in addition to preventative drugs produced "very striking" results, London researchers say.
The trial followed 6,000 children aged under 17 months in Burkina Faso and Mali.
Most of the 400,000 deaths from malaria each year are in the under-fives.
And the mosquito-borne disease is still a major health issue in many parts of sub-Saharan Africa.
This trial, published in the New England Journal of Medicine, focused on giving very young children a vaccine already in use and anti-malarial drugs at the time of year they are most vulnerable - often the rainy season (from June in Burkina Faso), when mosquitoes multiply.
-snip-
Read more: https://www.bbc.com/news/health-58332169