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Health

eppur_se_muova

(38,761 posts)

4. Wow, talk about well-precented ! Acetylation of salicylic acid gave aspirin, Diacetylation of morphine gave heroin.

Reply to OKIsItJustMe (Original post)

Fri Mar 14, 2025, 02:19 AM

Mar 14

Both have phenolic hydroxyl groups, although morphine has one saturated alcohol hydroxyl as well. Carnosic acid has two phenolic hydroxyl groups; acetylating both groups could justly be called one of the oldest tricks in the book -- aspirin and heroin were both invented in 1897.

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Wow, talk about well-precented ! Acetylation of salicylic acid gave aspirin, Diacetylation of morphine gave heroin. eppur_se_muova Mar 14 #4

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