Welcome to DU! The truly grassroots left-of-center political community where regular people, not algorithms, drive the discussions and set the standards. Join the community: Create a free account Support DU (and get rid of ads!): Become a Star Member Latest Breaking News Editorials & Other Articles General Discussion The DU Lounge All Forums Issue Forums Culture Forums Alliance Forums Region Forums Support Forums Help & Search

eppur_se_muova

(42,400 posts)
2. Some interesting reading about tissue transglutaminase (tTG) from Wikipedia ...
Sun May 3, 2026, 12:11 PM
May 3
https://en.wikipedia.org/wiki/Tissue_transglutaminase#Clinical_significance

The links to celiac disease should be interpreted very carefully ... when antibodies attack tTG (destroying or inactivating it), that is what causes the tissue breakdown. It is not the tTG itself; the tTG is more likely involved in routine tissue repair, and disabling that repair mechanism leads to the disease condition. So tTG is the good guy here, and (abnormal) antibodies are the bad guys. This is what is meant by an 'autoimmune disease' -- the body's own immune system attacks essential systems the body needs for good health. However, excess tTG activity may also be associated with several other diseases, but it's not entirely clear how, or to what extent. I would certainly hope tTG is denatured in the cooking process, as most enzymes are.

Recommendations

0 members have recommended this reply (displayed in chronological order):

Latest Discussions»Culture Forums»Cooking & Baking»What Is Meat Glue, and Is...»Reply #2