The problem when she was young was that she would only eat when everyone else was eating and she would not eat the special food that we got her. The original meds were of no help either. They came in this liquid gel cap that was too large for her to swallow and cutting it up or crushing it into food wasn't an option either. The most consistently reliable treatment has been the cortisol shots every 6-8 weeks. Our vet added acupuncture with B-12 on her last visit. She didn't like it much, but when she got home she was the most relaxed we've seen her in a long time. We have her two brothers/litter mates. They have a touch of the same thing and her feral mom had it too. She's doing fine in spite of it all. She purrs a lot and spends plenty of time in my lap too. We've been dealing with this for about 5 years now. Our vet is really sweet and she just charges us for the shots. We've spent a small fortune with her over the last ten years or so, so she takes care of us. We used to have 3 large dogs and about 8 cats at one point. Now we're just down to 3 cats. All the other ones got old and crossed over the rainbow bridge.