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Science

mr715

(4,061 posts)

10. Here is a link to it in uniprot

Reply to NNadir (Reply #9)

Sat May 9, 2026, 12:37 AM

Yesterday

https://www.uniprot.org/uniprotkb/Q8IWU9/entry

Q8IWU9

This is the human protein, but it shares amazing conservation. I think my form is still in the uncharacterized category but better model organisms share it and are pretty close to the mosquito.

It also happens to be a beautiful, symmetry homotetramer.

A former advisor of mine told me to stay away from serotonin research because it would "make me crazy," which is a spectacular line. I love him.

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I successfully used crispr to edit mosquitoes! [View all] mr715 Friday OP

My bug zapper does that too! erronis Friday #1

The handheld ones are very satisfying. mr715 Friday #2

Cool. What kind of gene did you insert? NNadir Friday #3

Tryptophan hydroxylase. mr715 Friday #4

That my friend, is very cool. I have to say that tryptophan has always been one of my favorite amino acids, probably... NNadir Yesterday #5

It is amazingly well conserved. mr715 Yesterday #6

Very cool. By "HELL" you mean histidine-glutamic acid-leucine-leucine or something else? NNadir Yesterday #7

Yeah. mr715 Yesterday #8

Cool. Do you happen to have the Uniprot accession number? I'd like to look into this one, nonprofessional interest... NNadir Yesterday #9

Here is a link to it in uniprot mr715 Yesterday #10

Very cool. I like your advisor's wit. Into what species of mosquito did you knock out the gene? NNadir Yesterday #11

Yes, it has a fully sequenced genome. mr715 21 hrs ago #12

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